Background: Menstrual disorders frequently affect the quality of life of adolescents and young adult women. Nutritional deficiency is considered one of the important factors that induce hypothalamic-pituitary-ovarian dysfunction. Breakfast as a part of healthful diet and lifestyle can positively impact children’s and young adult’s health and wellbeing. Daily eating habits significantly influence menstrual function in young women. Aim: The aim of the present study was to examine the effect of breakfast skipping on menstrual cycle among young females. Method and Material: A cross sectional descriptive design was used. The studied sample consisted of 300 female students from faculty of nursing in Menoufiya university, Egypt. Data were collected by using an interviewing questionnaire designed after literature review. Analysis of the findings was carried out using SPSS software package version 17. Results: There was an increase in the percentage of menstrual regularity in group one who have breakfast (89.1%) than group two who have skipped breakfast (83.9% p=0.206) . The results revealed a statistically significant difference regarding premenstrual abdominal pain, anorexia and premenstrual cramps (P= 0.035, 0.016 & 0.035 respectively), which decreased in group one than group two. But there was no difference between the two groups regarding the other items of premenstrual syndromes. Additionally, the current study results revealed that; dysmenorrhea was more in girls who skipped the breakfast meal than in those who had breakfast (P= 0.035). Conclusion: Skipping breakfast is related with irregular menstrual cycle and increase the incidence of dysmenorrhea, oligmenorrhea, premenstrual pain, anorexia and premenstrual cramps. But there was no effect on the other items of premenstrual syndromes.