Maternal Diet and Epigenetic Modifications at the Start of Life: Repercussions on the Development of Obesity

Objectives: Thus, the objective of the study was to evaluate the repercussions of the maternal diet and epigenetic changes in early life and its repercussions on the development of obesity. Methods: For this, a narrative review of a descriptive character was developed using the following descriptors: “Maternal diet”, “epigenetics” and “obesity”. The articles published between the years 2015 to 2020 were selected from the databases: Scientific Electronic Library Online (Scielo), National Library of Medicine (PubMed) and Virtual Health Library of the Ministry of Health (VHL). Results: It was observed that the intake of maternal high-fat diets promotes the appearance of epigenetic changes that favor the appearance of diseases, such as diabetes mellitus, in addition to increasing food intake, and consequently increasing body weight. Conclusions: Thus, the importance of healthy eating is observed during critical periods of development to prevent the onset of cardiometabolic diseases.


Matheus Santos de Sousa Fernandes, Camila Tenório Calazans, Gabriela Carvalho Jurema Santos

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