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Abstract

The Potential Impact of Helicobacter Pylori Infection on the Onset of Metabolic Disease

Background: Helicobacter pylori is a gram-negative, spiral-shaped, a pathogenic bacterium. Almost 50% of the world population is infected by this bacterium. Obesity, diabetes, and hypertension are multifactorial diseases that have also become a major public health problem of global significance and are found associated with several risk factors like H. pylori infection. It is also considered as a major risk factor in the onset of diseases such as obesity, diabetes, and hypertension.

Methodology: The study is designed to estimate the prevalence of H. pylori infections in the Rawalpindi region and to identify “the relationship between obesity, type-2 diabetes, hypertension, and H. pylori”. A cross-sectional study was conducted including 192 subjects from Rawalpindi, Pakistan”. Samples were obtained randomly from subjects for the detection of obesity, diabetes, hypertension, and H. pylori infection. Statistical analysis was done to establish associations of obesity, diabetes, and hypertension with H. pylori infection was assessed by various statistical tests using SPSS.

Results: The incidence of H. pylori infection was 44% in the sample population. The prevalence of obesity was observed 28%, type-2 diabetes was observed by 18% and hypertension was 22%. H. pylori infections among diabetic persons were observed 35% and 48% in non-diabetic subjects. The infection rate of H. pylori is observed high among hypertensive persons.

Conclusions: There is a significant association between obesity, hypertension, and H. pylori infection. There is no relationship between” association of diabetes “and H. pylori”. Large scale studies are required to assess “the prevalence of H. pylori infection”, and metabolic diseases.


Author(s):

Naveed Iqbal Soomro, Saeed Iqbal, Javed Iqbal, Muhammad Imran and Syeda Mariam Bakhtiar



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